Journal of Surgical Research 2014-05-01

Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats

Hongxia Gu, Min Yang, Xiaomin Zhao, Bing Zhao, Xuejun Sun, Xin Gao

Index: J. Surg. Res. 188(1) , 243-9, (2014)

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Abstract

Background Rhabdomyolysis is a leading cause of acute kidney injury. The pathophysiological process involves oxidative stress and inflammation. Hydrogen-rich saline (HRS) is an antioxidant and anti-inflammatory. This study explored the protective effect of pretreatment with HRS on the development of glycerol-induced rhabdomyolysis acute kidney injury.

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