ec 2.7.3.2

Names

[ Name ]:
ec 2.7.3.2

[Synonym ]:
Benzoic acid, 2,2'-[(2,5-dichloro-3,6-dioxo-1,4-cyclohexadiene-1,4-diyl)diimino]bis-
EINECS 232-585-5
atp: creatine n-phosphotransferase type iv
creatine kinase type iii
2,2'-[(2,5-Dichloro-3,6-dioxo-1,4-cyclohexadiene-1,4-diyl)diimino]dibenzoic acid
MFCD00130876
ck
creatine kinase type i
atp: creatine n-phosphotransferase type i
atp: creatine n-phosphotransferase type iii
atp: creatine n-phosphotransferase
cpk

Biological Activity

[Description]:

Creatine kinase catalyzes the reversible reaction of creatine and ATP to form phosphocreatine and ADP. Creatine kinase is a key enzyme for maintaining a constant ATP/ADP ratio during rapid energy turnover[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. McLeish MJ, et al. Relating structure to mechanism in creatine kinase. Crit Rev Biochem Mol Biol. 2005 Jan-Feb;40(1):1-20.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
629.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₂Cl₂N₂O₆

[ Molecular Weight ]:
447.225

[ Flash Point ]:
334.8±31.5 °C

[ Exact Mass ]:
446.007233

[ LogP ]:
4.44

[ Appearance of Characters ]:
salt-free, lyophilized powder | white

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.722

[ Storage condition ]:
−20°C

[ Water Solubility ]:
0.25 M glycyl-glycine, pH 7.4: soluble5.0mg/mL, clear, colorless to slightly yellow

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
35079090

Articles

Initial characterization of the human central proteome.

BMC Syst. Biol. 5 , 17, (2011)

On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitous...

The DNA sequence and biology of human chromosome 19.

Nature 428(6982) , 529-35, (2004)

Chromosome 19 has the highest gene density of all human chromosomes, more than double the genome-wide average. The large clustered gene families, corresponding high G + C content, CpG islands and dens...

A quantitative atlas of mitotic phosphorylation.

Proc. Natl. Acad. Sci. U. S. A. 105(31) , 10762-7, (2008)

The eukaryotic cell division cycle is characterized by a sequence of orderly and highly regulated events resulting in the duplication and separation of all cellular material into two newly formed daug...