Chemistry Letters

Regioselective reduction of polyketones on silica gel surface with borane–trimethylamine complex

S Gohzu, M Tada

Index: Gohzu, Shun-ichi; Tada, Masahiro Chemistry Letters, 1986 , p. 61 - 64

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Citation Number: 8

Abstract

Steroidal diones and trione, bicyclic diones (7 and 8) and a tricyclic dione were adsorbed on silica gel and reduced with BH 3. NMe 3. The carbonyl groups at C-3 of the steroids, at C-4 of 7 and at C-3 of 8 were reduced regioselectively. The FT-IR spectra of 5α-and 5β- androstane-3, 17-dione adsorbed on silica gel were measured.

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