Tetrahedron letters

Synthesis of α-aminoketones via selective reduction of acyl cyanides

A Pfaltz, S Anwar

Index: Pfaltz, Andreas; Anwar, Saeed Tetrahedron Letters, 1984 , vol. 25, # 28 p. 2977 - 2980

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Citation Number: 37

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Reduction of acyl cyanides with zinc in acetic acid in the presence of excess acetic anhydride leads to N-acetyl-α-aminoketones in good yields. An efficient three-step synthesis of 5-aminolevulinic acid by this method is described. ... J. Org. Chem., 37 (1972), p. 318 According to a ...

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