Catalytic enantioselective cyclopropanation with bis (halomethyl) zinc reagents. II. The effect of promoter structure on selectivity
SE Denmark, BL Christenson, SP O'Connor
Index: Denmark, Scott E.; Christenson, Beritte L.; O'Connor, Stephen P. Tetrahedron Letters, 1995 , vol. 36, # 13 p. 2219 - 2222
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Citation Number: 73
Abstract
The catalytic, enantioselective cyclopropanation of cinnamyl alcohol has been accomplished with bis (iodomethyl) zinc in the presence of chiral bis (sulfonamides) derived from cyclohexanediamine. An extensive survey of diamine and sulfonamide structure has revealed a marked sensitivity to the spatial relationship of the amine groups, but only a modest dependence on the sulfonamide residue.
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