High activity of an Fe–tfda (tfda= 2-aminomethyltetrahydrofuran-N, N-diacetic acid) complex for hydroxylation at the aromatic and alkane rings of 2′-deoxyguanosine …
Y Nishida, S Ito
Index: Nishida, Yuzo; Ito, Sayo Journal of the Chemical Society, Chemical Communications, 1995 , # 12 p. 1211 - 1212
Full Text: HTML
Citation Number: 2
Abstract
An iron (III) complex with tfda (2-aminomethyltetrahydrofuran-N, N-diacetic acid) exhibits high activity for hydroxylation at the 8 and 2′ positions of deoxyguanosine in the presence of hydrogen peroxide; this demonstrates that a facile transformation from deoxyribonucleotide to ribonucleotide in vivo may be possible.
Related Articles:
[Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301]
[Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301]
[Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301]
[Kohda, Kohfuku; Baba, Kunihisa; Kawazoe, Yutaka Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 5 p. 2298 - 2301]