Direct ni mediated synthesis of ketones from acyl bromides and grignard reagents
C Malanga, LA Aronica, L Lardicci
Index: Malanga, Corrado; Aronica, Laura A.; Lardicci, Luciano Tetrahedron Letters, 1995 , vol. 36, # 50 p. 9185 - 9188
Full Text: HTML
Citation Number: 24
Abstract
a catalytic amount of NidppeCl2 converts an acyl bromide directly into ketones at 0° C in THF in the presence of a Grignard reagent. The described procedure represents a useful way to afford dialkyl, diaryl or alkyl aryl ketones as well as 1, 2-diketones. In the adopted reaction conditions double bonds, esters and ketones are unaffected.
Related Articles:
Transition metal-mediated oxidations utilizing monomeric iodosyl-and iodylarene species
[Yusubov, Mekhman S.; Nemykin, Victor N.; Zhdankin, Viktor V. Tetrahedron, 2010 , vol. 66, # 31 p. 5745 - 5752]
Ion exchange catalysis in oxidation of organic compounds with KMnO4
[Shaabani, Ahmad; Teimouri, Fatemeh; Lee, Donald G. Synthetic Communications, 2003 , vol. 33, # 6 p. 1057 - 1065]
[Farhadi; Ansari Journal of the Iranian Chemical Society, 2011 , vol. 8, # 2 p. 470 - 476]
Hydration of alkynes by a PtCl4-CO catalyst
[Baidossi, Wael; Lahav, Michal; Blum, Jochanan Journal of Organic Chemistry, 1997 , vol. 62, # 3 p. 669 - 672]
Hydration of alkynes by a PtCl4-CO catalyst
[Baidossi, Wael; Lahav, Michal; Blum, Jochanan Journal of Organic Chemistry, 1997 , vol. 62, # 3 p. 669 - 672]