A highly efficient protocol for the synthesis of N-aryl nucleobases using zinc oxide in ionic liquids

…, A Khalafi-Nezhad, AR Moosavi-Zare…

Index: Zare; Hasaninejad; Khalafi-Nezhad; Moosavi-Zare; Beyzavi; Khedri; Asadi; Hayati; Asifi Journal of the Iranian Chemical Society, 2010 , vol. 7, # 2 p. 461 - 469

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Citation Number: 10

Abstract

Abstract A highly efficient and simple method for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases via N arylation of nucleobases using zinc oxide in 1- butyl-3-methylimidazolium bromide ([bmim] Br) under microwave as well as thermal conditions is described. In both conditions, the title compounds were produced in high to excellent yields and in short reaction times.