New approach for the synthesis of 1-aryl-and 1-heteroaryl-5-nitrouracil derivatives
A Gondela, K Walczak
Index: Gondela, Andrzej; Walczak, Krzysztof Tetrahedron, 2007 , vol. 63, # 13 p. 2859 - 2864
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Citation Number: 9
Abstract
1-(2, 4-Dinitrophenyl)-5-nitrouracil and its 3-methyl derivatives were synthesized and used as substrates in reaction with aromatic amines and amino pyridines. In the reaction of aniline with 1-(2, 4-dinitrophenyl)-5-nitrouracil, only the acyclic adduct was isolated. When 1-(2, 4- dinitrophenyl)-3-methyl-5-nitrouracil was treated with aniline and other aromatic amines or amino pyridines, the desired 1-aryl-5-nitrouracil derivatives were obtained in satisfactory ...
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