Tandem Cyclization of α-Cyano α-Alkynyl Aryl Ketones Induced by tert-Butyl Hydroperoxide and Tetrabutylammonium Iodide
YC Wong, CT Tseng, TT Kao, YC Yeh, KS Shia
Index: Wong, Ying-Chieh; Tseng, Chen-Tso; Kao, Tzu-Ting; Yeh, Yu-Cheng; Shia, Kak-Shan Organic Letters, 2012 , vol. 14, # 23 p. 6024 - 6027
Full Text: HTML
Citation Number: 29
Abstract
The radical cascade protocol of the α-cyano α-TMS/aryl-capped alkynyl aryl ketones promoted by tert-butyl hydroperoxide under catalysis with tetrabutylammonium iodide in refluxing benzene has been developed, leading to the construction of a variety of highly functionalized [6, 6, 5] tricyclic frameworks in an efficient manner.
Related Articles:
An efficient protocol for the acylation of t-butanol in the presence of samarium diiodide
[Jia, Xueshun; Zhu, Li; Li, Qing; Li, Jian; Li, Dafeng; Li, Shaoyu Journal of Chemical Research, 2007 , # 4 p. 203 - 204]
[Kleeberg, Christian; Dang, Li; Lin, Zhenyang; Marder, Todd B. Angewandte Chemie, International Edition, 2009 , vol. 48, p. 5350 - 5354 Angewandte Chemie, 2009 , vol. 121, p. 5454 - 5458]
A mild protocol for the conversion of simple esters to tert-butyl esters
[Stanton, Matthew G.; Gagne, Michel R. Journal of Organic Chemistry, 1997 , vol. 62, # 23 p. 8240 - 8242]
[Lee, Jae In Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 5 p. 1765 - 1768]
[Dohi, Souya; Moriyama, Katsuhiko; Togo, Hideo European Journal of Organic Chemistry, 2013 , # 34 p. 7815 - 7822]