An efficient protocol for the acylation of t-butanol in the presence of samarium diiodide

X Jia, L Zhu, Q Li, J Li, D Li, S Li

Index: Jia, Xueshun; Zhu, Li; Li, Qing; Li, Jian; Li, Dafeng; Li, Shaoyu Journal of Chemical Research, 2007 , # 4 p. 203 - 204

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Abstract

Samarium diiodide (SmI2) promotes the rapid acylation of t-butanol with a variety of acid chlorides under neutral conditions to afford cleanly the corresponding t-butyl esters in excellent yields. ... Keywords: acylation, samarium diiodide, t-butanol, t-butyl esters, acid chlorides ... Numerous naturally occurring as well as synthetically and biologically interesting compounds like nucleosides, carbohydrates, carbocycles, steroids etc. have hydroxyl functions as part of ...