On water and in air: fast and highly chemoselective transfer hydrogenation of aldehydes with iridium catalysts

…, A Zanotti??Gerosa, F Hancock, D Vinci…

Index: Wu, Xiaofeng; Liu, Jianke; Li, Xiaohong; Zanotti-Gerosa, Antonio; Hancock, Fred; Vinci, Daniele; Ruan, Jiwu; Xiao, Jianliang Angewandte Chemie - International Edition, 2006 , vol. 45, # 40 p. 6718 - 6722

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Citation Number: 150

Abstract

shown in Table 1, the reaction was slow for all four complexes. However, the introduction of the readily available ethylenediamine (en) brought about a significant ligand-acceleration effect on the rates and, most remarkably, the monotosylated analogue Ts (en) led to around a 1000-fold increase in rate (Table 1, entries 3, 11, and 14).[13]