Electrochemical Phenylselenoetherification as a Key Step in the Synthesis of (±)??Curcumene Ether

D Stevanović, A Pejović, IS Damljanović…

Index: Stevanovic, Dragana; Pejovic, Anka; Damljanovic, Ivan S.; Vukicevic, Mirjana D.; Dobrikov, Georgi; Dimitrov, Vladimir; Denic, Marija S.; Radulovic, Niko S.; Vukicevic, Rastko D. Helvetica Chimica Acta, 2013 , vol. 96, # 6 p. 1103 - 1110

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Citation Number: 2

Abstract

Abstract Two variants of a new pathway for the synthesis of (±)-curcumene ether are described. The key steps in these procedures are intramolecular cyclizations of 6-methyl-2- (4-methylphenyl) hept-6-en-2-ol and 2-methyl-6-(4-methylphenyl) hept-6-en-2-ol by means of an electrochemically generated phenylselenyl cation. This synthetic approach provides significantly better yields than the previously reported protocols.