Formation of α??pyridones from α??acylbenzyl cyanides

JFM Wajon, JF Arens

Index: Wajon; Arens Recueil des Travaux Chimiques des Pays-Bas, 1957 , vol. 76, p. 65,71

Full Text: HTML

Citation Number: 8

Abstract

Abstract Heating α-acetylbenzyl cyanide I with a mixture of acetic acid and sulphuric acid leads to the formation of the α-pyridone IV, formed by condensation of the amide II with the ketone III, both of which originate from the cyanide I (see scheme 1). A similar reaction has been observed with some other α-acylbenzyl cyanides.