Synthesis

A suzuki-miyaura approach to a series of forensically relevant pyridines

D Błachut, Z Czarnocki, K Wojtasiewicz

Index: Blachut, Dariusz; Czarnocki, Zbigniew; Wojtasiewicz, Krystyna Synthesis, 2006 , # 17 p. 2855 - 2864

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Citation Number: 10

Abstract

Abstract A convenient and general method for the preparation of sixteen 3, 5- diarylsubstituted 2, 4-and 2, 6-dimethylpyridines of high forensic importance is described. The Suzuki cross-coupling reaction between a range of ring-substituted phenylboronic acids and 3, 5-dibromo-2, 4-dimethylpyridine and 3, 5-dibromo-2, 6-dimethylpyridine was used as a key step.