Tetrahedron letters

Efficient synthesis of substituted benzenes from 1, 3-dienes or 1, 4-cyclohexadienes with KMnO 4 under mild conditions

CM McBride, W Chrisman, CE Harris, B Singaram

Index: McBride, Christopher M.; Chrisman, Will; Harris, Clifford E.; Singaram, Bakthan Tetrahedron Letters, 1999 , vol. 40, # 1 p. 45 - 48

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Citation Number: 14

Abstract

Potassium permanganate absorbed on alumina is used to oxidize 1, 4-cyclohexadienes to the corresponding aromatic compounds. Intermolecular Diels-Alder reactions followed by dehydrogenation of the products with potassium permanganate supported on alumina gives an efficient two step synthesis of highly substituted aromatic compounds from acyclic precursors.

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