Tetrahedron Letters

Cesium carbonate promoted aerobic oxidation of arylacetamides: an efficient access to N-substituted α-keto amides

B Song, S Wang, C Sun, H Deng, B Xu

Index: Song, Bingrui; Wang, Siyuan; Sun, Caiyun; Deng, Hongmei; Xu, Bin Tetrahedron Letters, 2007 , vol. 48, # 51 p. 8982 - 8986

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Citation Number: 49

Abstract

A novel cesium carbonate promoted aerobic oxidation reaction to prepare N-substituted α- keto amides in the presence of catalytic amount of tetra-n-butylammonium bromide was described. This reaction provides a very simple and convenient route from easily available arylacetamides in good to high yields.

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