4-(Aminoacylamido)-s-hydrindacenes and related compounds: Synthesis and pharmacological screening
…, J Holubek, M Bartošová, M Protiva
Index: Vejdelek; Holubek; Bartosova; Protiva Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 12 p. 3297 - 3305
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Abstract
Abstract Chloracylamido derivatives IIIa-Va were obtained by acylation of 4-amino-s- hydrindacene with chloroacetyl chloride, 2-chloropropionyl chloride and 3-chloropropionyl chloride; their reactions with excessive diethylamine, pyrrolidine, piperidine and morpholine afforded the title compounds IIIbcde-Vbcde. A reaction of 4-amino-s-hydrindacene with benzoyl isothiocyanate gave 1-benzoyl-3-(s-hydrindacen-4-yl) thiourea (VI) whose mild ...
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