Organic letters

Convergent Synthesis of Geometrically Disassembling Dendrimers using Cu (I)-Catalyzed C− O Bond Formation

…, ML Szalai, CS Shanahan, DV McGrath

Index: Polaske, Nathan W.; Szalai, Michael L.; Shanahan, Charles S.; McGrath, Dominic V. Organic Letters, 2010 , vol. 12, # 21 p. 4944 - 4947

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Citation Number: 14

Abstract

The convergent synthesis of geometrically degradable dendrimers based on the 2, 4-bis (hydroxymethyl) phenol subunit is presented. The key step of the synthetic scheme involves the CuI/3, 4, 7, 8-tetramethyl-1, 10-phenanthroline-catalyzed coupling of aryl iodides and alcohols. The synthesis and disassembly of these compounds is discussed.

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