2-Lithio-N-methylpiperidine and 2-lithio-N-methylpyrrolidine: Configurationally and chemically stable unchelated. alpha.-aminoorganolithiums
RE Gawley, Q Zhang
Index: Gawley, Robert E.; Zhang, Qianhui Journal of the American Chemical Society, 1993 , vol. 115, # 16 p. 7515 - 7516
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Citation Number: 74
Abstract
The past 10-15 years has seen a surge of interest in the use of functionalized organolithiums in organic synthesis.' An important category of such systems includes a-heteroatom- substituted organolithiums, especially when the heteroatom is oxygen or nitrogen. a-Alkoxyorganolithiums rose to prominence after it was demonstrated2 that they are configurationally stable at low temperature, making them useful intermediates in asymmetric synthesis.3 a- ...
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