Continuous Flow Production of Thermally Unstable Intermediates in a Microreactor with Inline IR-Analysis: Controlled Vilsmeier–Haack Formylation of Electron-Rich …

SBAMW van den Broek, JR Leliveld…

Index: Organic Process Research and Development, , vol. 16, # 5 p. 934 - 938

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Citation Number: 25

Abstract

... Scheme 1). In batch, 2-formylpyrrole (6) is prepared in a three-step procedure, first allowing ... In flow chemistry, scaling out is a one-to-one process in most cases, eliminating the need ... The organic layer was dried over MgSO 4 , filtered, and concentrated in vacuo (700 mbar, 40 °C ...

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