Detailed rate studies on the Wittig reaction of nonstabilized phosphorus ylides via phosphorus-31, proton, carbon-13 NMR spectroscopy. Insight into kinetic vs. …

…, MS Mutter, RR Inners, HR Almond Jr

Index: Maryanoff, Bruce E.; Reitz, Allen B.; Mutter, Martin S.; Inners, Ruth R.; Almond, Harold R. Jr. Journal of the American Chemical Society, 1985 , vol. 107, # 4 p. 1068 - 1070

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Abstract

* COZ substrates gave comparable levels of 14C incorporation, but only L-serine and D- glycerate gave positive incorporations of tritium. I4C incorporations were somewhat more responsive to increasing amounts of D-glycerate supplied than L-serine (experiments 8 and 9 vs. 11-13), but relative tritium retentions were remarkably similar, albeit low (ca. lo%, cf. experiments 8 and 1 l), presumably owing to racemization and redox rates competitive ...

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