First Kumada reaction of alkyl chlorides using N-heterocyclic carbene/palladium catalyst systems

AC Frisch, F Rataboul, A Zapf, M Beller

Index: Frisch, Anja C.; Rataboul, Franck; Zapf, Alexander; Beller, Matthias Journal of Organometallic Chemistry, 2003 , vol. 687, # 2 p. 403 - 409

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Citation Number: 87

Abstract

For the first time it is shown that N-heterocyclic carbenes are suitable ligands for the palladium-catalyzed coupling of alkyl chlorides with aryl Grignard reagents. A variety of simple as well as functionalized primary alkyl chlorides provide the corresponding alkyl benzenes in general in good to very good yield. By comparing the 1, 3-dimesitylimidazol-2- ylidene (IMes) palladium (0) naphthoquinone complex with the previously known ...