Synthesis of N-aryl derivatives of succinimide and phthalimide

SI Zav'yalov, AG Zavozin, LB Kulikova…

Index: Zav'yalov; Zavozin; Kulikova; Ezhova; Kravchenko Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 1 p. 43 - 44

Full Text: HTML

Citation Number: 3

Abstract

The N-aryl derivatives of succinimide and phthalimide exhibit fungicide action [1] and hypolipidemic activity [2]. These derivatives are obtained by heating aromatic amines with succinic (I) and phthalic (II) anhydrides in cymene [2] or in a mixture of AcOH, AcONa, and Ae20 [3]. Methods also have been reported for synthesizing these derivatives by in- teraction of arylamines with dichloroanhydride of succinic acid [4], N-hydroxyphthalimide [5], and thiophthalic anhy- dride [6], or by ...

Related Articles:

Palladium on Carbon: An Efficient, Heterogeneous and Reusable Catalytic System for Carbonylative Synthesis of N??Substituted Phthalimides

[Khedkar, Mayur V.; Khan, Shoeb R.; Sawant, Dinesh N.; Bagal, Dattatraya B.; Bhanage, Bhalchandra M. Advanced Synthesis and Catalysis, 2011 , vol. 353, # 18 p. 3415 - 3422]

The reaction of phthalidylidene dichloride with primary amines. Synthesis and X-ray molecular structure of N-substituted phthalisoimides

[Guirado, Antonio; Zapata, Andres; Ramirez De Arellano, M. Carmen Tetrahedron, 1997 , vol. 53, # 14 p. 5305 - 5324]

Synthesis and Potent Tumour Necrosis Factor?螃? Production Inhibitory Activity of N??Pyridinylphthalimides and Derivatives

[Collin; Robert; Robert-Piessard; Le Baut; Bobin-Dubigeon; Vernhet; Lang; Petit Pharmacy and Pharmacology Communications, 1998 , vol. 4, # 1 p. 27 - 31]

New anti-inflammatory N-pyridinyl (alkyl) phthalimides acting as tumour necrosis factor-α production inhibitors

[Collin, Xavier; Robert, Jean-Michel; Wielgosz, Gaetane; Le Baut, Guillaume; Bobin-Dubigeon, Christine; Grimaud, Nicole; Petit, Jean-Yves European Journal of Medicinal Chemistry, 2001 , vol. 36, # 7-8 p. 639 - 649]

New anti-inflammatory N-pyridinyl (alkyl) phthalimides acting as tumour necrosis factor-α production inhibitors

[Collin, Xavier; Robert, Jean-Michel; Wielgosz, Gaetane; Le Baut, Guillaume; Bobin-Dubigeon, Christine; Grimaud, Nicole; Petit, Jean-Yves European Journal of Medicinal Chemistry, 2001 , vol. 36, # 7-8 p. 639 - 649]

More Articles...