Enantioselective bromolactonization of cis-1, 2-disubstituted olefinic acids using an amino-thiocarbamate catalyst
CK Tan, C Le, YY Yeung
Index: Tan, Chong Kiat; Le, Chencheng; Yeung, Ying-Yeung Chemical Communications, 2012 , vol. 48, # 46 p. 5793 - 5795
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Citation Number: 60
Abstract
A facile, highly regio-and enantioselective amino-thiocarbamate-catalyzed bromolactonization of cis-1, 2-disubstituted olefinic acids has been developed. The use of the enantio-enriched lactones in the synthesis of chiral synthetic intermediates is also demonstrated.
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