Capsaicinoids: their separation, synthesis, and mutagenicity

…, DL Nagel, PJ Reilly, T Lawson, J Sharpe…

Index: Gannett, Peter M.; Nagel, Donald L.; Reilly, Pam J.; Lawson, Terence; Sharpe, Jody; Toth, Bela Journal of Organic Chemistry, 1988 , vol. 53, # 5 p. 1064 - 1071

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Citation Number: 134

Abstract

Capsaicin (lb), the pungent ingredient in many varieties of Capsicum has recently been implicated as a possible carcinogen. When obtained from natural sources lb is always accompanied by a number of related homologues. We have isolated seven of these homologues, characterized them, and synthesized them by a general and unique route developed in our laboratories. Also reported are mutagenicity data for lb and an extract of ...