Synthesis and antimicrobial activity of thioxopyrimidines and related derivatives

…, FA Eid, MAA El-Nassag, G El-Sherbeny…

Index: El-Agrody, Ahmed M.; Ali, Fawzy M.; Eid, Fathy A.; El-Nassag, Mohammed A. A.; El-Sherbeny, Gamal; Bedair, Ahmed H. Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 4 p. 839 - 864

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Citation Number: 5

Abstract

The interaction of thiourea with activated cyanoolefins under different reaction conditions were studied, in which a variety of thiopyrimidines (8, 9, 12, 18, 20, & 21) and related derivatives (10, 11, 14, 16, & 17) were obtained respectively. Also, the reactions of thiopyrimidines (8, 9) with different electrophilic and nucleophilic reagents were reported. IR, 1H NMR, 13 C NMR and mass spectra for the newly synthesized compounds were ...