Asymmetric total syntheses of (-)-and (+)-strychnine and the Wieland-Gumlich aldehyde
…, LE Overman, G Pairaudeau
Index: Knight, Steven D.; Overman, Larry E.; Pairaudeau, Garry Journal of the American Chemical Society, 1995 , vol. 117, # 21 p. 5776 - 5788
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Citation Number: 124
Abstract
Abstract: The fist asymmetric total syntheses of (-)-strychnine, ent-strychnine, and the Wieland-Gumlich aldehyde are described with full experimental details. The total synthesis of (-)-strychnine was realized in 24 steps and 3% overall yield from (1R, 4S)-(f)-4-hydroxy- ...
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