Synthetic Communications

Reduction of isophorone with sodium borohydride: change in regioselectivity with hydrotropes

M Laxman, MM Sharma

Index: Laxman, Mahalaxmi; Sharma, Man Mohan Synthetic Communications, 1990 , vol. 20, # 1 p. 111 - 117

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Citation Number: 20

Abstract

ABSTRACT : Preferential 1,4- reduction of isophorone by sodium borohydride occurs in the presence of hydrotropes such as polyalkylene glycols. An anomalous effect of temperature was also observed using sodium salicylate as hydrotrope. ... Since the pioneering work of Neuberg', the term hydrotropy has been used to ... Very recently, a minimum hydrotrope concentration has been proposed5, formally ... Figure 1 : Reduction of isophorone by sodium borohydride

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