Preparation of (S)-N-Substituted 4-Hydroxy-pyrrolidin-2-ones by Regio-and Stereoselective Hydroxylation with Sphingomonas sp. HXN-200
D Chang, B Witholt, Z Li
Index: Organic Letters, , vol. 2, # 24 p. 3949 - 3952
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Citation Number: 44
Abstract
... Volume: Page: ... Organic Letters. ... crystallization from n-hexane/ethyl acetate (2:1). In summary, we have developed a simple and practical synthesis of (S)-N-substituted 4-hydroxy-pyrrolidin- 2-ones by hydroxylation of the corresponding pyrrolidin-2-ones with ...
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