Tetrahedron letters

Studies of the asymmetric [2+ 2] cycloaddition of silylketenes and aldehydes employing Ti-TADDOL catalysts

HW Yang, D Romo

Index: Yang, Hong Woon; Romo, Daniel Tetrahedron Letters, 1998 , vol. 39, # 19 p. 2877 - 2880

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Citation Number: 38

Abstract

Ti-TADDOL catalysts provide good reactivity and moderate enantioselectivity in the asymmetric [2+ 2] cycloaddition of silyl ketenes and aldehydes. The effects of potential bidentate chelation of benzyloxy substituted aldehydes and of the steric size of the ketene silyl group were studied.

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