Palladium-Catalyzed Cascade Reactions of 1-(3-Arylprop-2-ynyloxy)-2-bromo Benzene Derivatives with Organoboron Compounds

…, G Fabrizi, A Goggiamani, F Marinelli

Index: Arcadi, Antonio; Blesi, Federico; Cacchi, Sandro; Fabrizi, Giancarlo; Goggiamani, Antonella; Marinelli, Fabio Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9700 - 9708

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Citation Number: 12

Abstract

Applications of the cascade cyclocarbopalladation reaction followed by Suzuki–Miyaura coupling reactions of the readily available aryl-substituted propargylic aryl ethers with arylboronic acid and potassium trans-β-styryltrifluoroborate accomplish a new versatile entry in the synthesis of benzofuran derivatives. Notably, a new approach to the challenging synthesis of C3 functionalized 2-unsubstituted benzofurans has been developed by a ...