Chemistry Letters

A facile synthesis of 1, 3-cycloalkadiones.

I Nishiguchi, T Hirashima, T Shono, M Sasaki

Index: Nishiguchi, Ikuzo; Hirashima, Tsuneaki; Shono, Tatsuya; Sasaki, Manji Chemistry Letters, 1981 , p. 551 - 554

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Citation Number: 8

Abstract

1, 3-Cycloalkadiones were prepared by the reaction of l, 2-bis (trimethylsiloxy) cycloalkenes with chloromethyl methyl ether followed by treatment of the resulting 2-hydroxy-2- methoxymethyl cycloalkanones with potassium hydrogen sulfate. The first step of the reactions was effectively catalyzed by active zinc reagents prepared from zinc–copper and alkyl iodides.

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