Bioorganic & medicinal chemistry letters

A novel fluorescent sensor for triplex DNA

E Lu, X Peng, F Song, J Fan

Index: Lu, Erhu; Peng, Xiaojun; Song, Fengling; Fan, Jiangli Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 2 p. 255 - 257

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Citation Number: 16

Abstract

A triplex DNA fluorescent sensor based on PET is described. The sensor takes 4- aminonaphthalimide as a reporting group and a triplex-select intercalator as a recognizing group. The results show that it is a selective sensor for T· AT triplex DNA in compared with duplex and ssDNA by fluorescence enhancement in PIPES 20 buffer.

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