Glycolamide esters of N-acylamino acids and peptides
FHC Stewart
Index: Stewart,F.H.C. Australian Journal of Chemistry, 1965 , vol. 18, p. 1089 - 1094
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Citation Number: 7
Abstract
Abstract The glycolamide esters, RNHCHR'CO 2 CH 2 CONH 2, of several N-acylamino acids have been prepared. Model experiments indicate that the glycolamide group possesses weak acylating ability in simple peptide coupling reactions, but that it can be dehydrated under mild conditions with formation of cyanomethyl esters, which are known to be active acylating agents. The possible application of the glycolamide derivatives in ...
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