Chemical Communications

Intramolecular radical hydrosilylation—the first radical 5-endo-dig cyclisation

S Amrein, A Studer

Index: Amrein, Stephan; Studer, Armido Chemical Communications, 2002 , # 15 p. 1592 - 1593

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Citation Number: 21

Abstract

Recently, we presented the first results on the radical hydrosilylation using silylated cyclohexadienes of type 1. 5 The bisvinylic methylene group acts as the hydrogen donor in these chain reactions. 6,7 Thus, H-transfer leads to a cyclohexadienyl radical 2, which subsequently rearomatizes to provide the tert-butyldimethylsilyl radical and arene 3 (Scheme 1). Silyl radical addition onto the alkene leads to a β-silylalkyl radical, which upon reduction with 1 eventually affords ...

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