Preparation of enamines by the reaction of ketones and secondary amines with silylating agents
Y Yamamoto, C Matui
Index: Yamamoto, Yasushi; Matui, Chinami Journal of Organic Chemistry, 1998 , vol. 63, # 2 p. 377 - 378
Full Text: HTML
Citation Number: 7
Abstract
Enamines are useful intermediates in organic synthesis, and many methods for their preparation have been developed. 1 Of these protocols, the azeotropic removal of water in benzene or toluene2 is the most common, though methods using molecular sieves, 3 TiCl4, 4 and metal amides5 have also been reported. Franck and Weinreb were the first to report the use of N-silylamines for the preparation of enamines from aldehydes and ketones. 6 ...
Related Articles:
The alkylation of imine anions formation of enamines
[Heiszwolf,G.J.; Kloosterziel,H. Recueil des Travaux Chimiques des Pays-Bas, 1970 , vol. 89, p. 1217 - 1228]