Inhibitors of acyl-CoA: cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of …

…, JA Picard, DR Sliskovic, BD Roth, RL Stanfield…

Index: Lee; Roark; Picard; Sliskovic; Roth; Stanfield; Hamelehle; Bousley; Krause Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 3 p. 289 - 294

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Citation Number: 21

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Sulfoacetic acid, phosphoramidate, and phosphonamide analogs of the ACAT inhibitors, CI-999 and CI-1011 were synthesized. The structure-activity relationships of these compounds as ACAT inhibitors are described. ... Sulfoacetic acid, phosphoramidate, and phosphonamide ...