A regiocontrolled synthesis of N7-and N9-guanine nucleosides
P Garner, S Ramakanth
Index: Garner, Philip; Ramakanth, Sarabu Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1294 - 1298
Full Text: HTML
Citation Number: 87
Abstract
The reaction of 2-0-acetylated and 2-0-benzoylated glycosides 3a, b/4a, b with silylated p- acetylguanine 7 selectively gave"'-guanine nucleosides 8a, b/Sa, b under kinetically controlled conditions (SnC14/CH3CN, room temperature), whereas 2-0-benzoylated glycosides 3b/4b selectively gave the isomeric Ns-guanine nucleosides lob/1 lb under thermodynamically controlled conditions (TMSOTf/(CH, Cl),, reflux). Unambiguous ...
Related Articles:
[Wright, George E.; Dudycz, Lech W. Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 175 - 181]
[Wright, George E.; Dudycz, Lech W. Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 175 - 181]
[Bookser, Brett C.; Raffaele, Nicholas B. Journal of Organic Chemistry, 2007 , vol. 72, # 1 p. 173 - 179]
Improved procedure for the regiospecific synthesis of 2′-deoxyribonucleosides
[Baud; Chavis; Lucas; Imbach Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4437 - 4440]
Improved procedure for the regiospecific synthesis of 2′-deoxyribonucleosides
[Baud; Chavis; Lucas; Imbach Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4437 - 4440]