Tetrahedron Letters

Improved procedure for the regiospecific synthesis of 2′-deoxyribonucleosides

MV Baud, C Chavis, M Lucas, JL Imbach

Index: Baud; Chavis; Lucas; Imbach Tetrahedron Letters, 1990 , vol. 31, # 31 p. 4437 - 4440

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Citation Number: 21

Abstract

Abstract 2′-Deoxyribonucleosides are regiospecifically synthesized in high yields by catalyzing with KI-dibenzo-18-crown-6 PTC the condensation between unprotected silylated purines and pyrimidines and the appropriate easily available 2-deoxyribofuranosyl or pyranosyl sugar derivatives.