Chemistry of novel compounds with a multifunctional carbon structure. 5. Molecular design of versatile building blocks for aliphatic monofluoro molecules by …

Y Takeuchi, K Nagata, T Koizumi

Index: Takeuchi, Yoshio; Nagata, Kazuhiro; Koizumi, Toru Journal of Organic Chemistry, 1989 , vol. 54, # 23 p. 5453 - 5459

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Citation Number: 46

Abstract

Three kinds of doubly functionalized monofluoromethylene fragments, 1-fluoro-1-nitro-1- (phenylsulfony1) alkanes (lo), 2-fluoro-2-(phenylsulfonyl) alkanoic esters (1 l), and 2-fluoro-2- nitroalkanoic esters (12), potentially versatile building blocks for the general synthesis of various aliphatic monofluoro molecules, were prepared from the corresponding difunctional compounds 1-3 by monoalkylations (R) and selective fluorinations. The interconversion or ...

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