QSAR modeling of synthesized 3-(1, 3-benzothiazol-2-yl) 2-phenyl quinazolin-4 (3H)-ones as potent antibacterial agents

P Sharma, A Kumar, P Kumari, J Singh…

Index: Sharma, Pratibha; Kumar, Ashok; Kumari, Prerna; Singh, Jitendra; Kaushik Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1136 - 1148

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Citation Number: 9

Abstract

Abstract Present communication elicits the designing and synthesis of 3-(1, 3-benzothiazol-2- yl) 2-phenyl quinazolin-4 (3 H)-ones as potential antibacterial agents. A number of substituted 2-amino benzothiazoles, 2-amino-5-[(E)-phenyl diazenyl] benzoic acid, and 2- phenyl-4 H benzo [d][1, 3] oxazin-4-one were synthesized as the precursor substrates. The compounds were synthesized in excellent yields and the structures were corroborated on ...