Efficient synthesis routes for various phthalimido phosphor esters as antimicrobial agents in terms of structure–activity relationship
WM Abdou, RE Khidre
Index: Abdou, Wafaa Mahmoud; Khidre, Rizk E. Monatshefte fur Chemie, 2010 , vol. 141, # 2 p. 219 - 228
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Citation Number: 14
Abstract
Abstract A series of phthalimido phosphor derivatives—α-amino-phosphonates, amidophosphonates, phosphonic acid diamides, and oxadiazaphospholes—were prepared by applying different types of phosphorus (III) reagents to 2-methoxy-1 H-isoindole-1, 3 (2 H)- dione and 2-anilino-1 H-isoindole-1, 3 (2 H)-dione. On the basis of bioassay results, some of the new phosphoryl imides could be considered as lead molecules to be modified in order ...
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