Phosphorus pentoxide as an efficient catalyst for the tetrahydropyranylation of alcohols under solvent-free conditions

H Eshghi, P Shafieyoon

Index: Eshghi, Hossein; Shafieyoon, Parvaneh Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 10 p. 2149 - 2152

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Citation Number: 16

Abstract

A facile and efficient method for the preparation of tetrahydropyranyl ethers from alcohols is improved in solvent-free media. These reactions are catalyzed by P2O5 and afford various tetrahydropyranyl ethers in shorter reaction time, with good to excellent yields (75–95%) at room temperature. This method is also compatible with substrates containing acid-sensitive functional groups.