Tetrahedron

Ligand creation via linking—a rapid and convenient method for construction of novel supported PyOX-ligands

MJ Oila, JE Tois, AMP Koskinen

Index: Oila, Markku J.; Tois, Jan E.; Koskinen, Ari M.P. Tetrahedron, 2005 , vol. 61, # 45 p. 10748 - 10756

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Citation Number: 13

Abstract

A novel supported amino alcohol linker was synthesized and utilized for attachment of picolinic acid derivatives onto different supports. When the resin bound molecule was further activated, the PyOX-moiety could be constructed reliably in enantiopure form. Furthermore, an efficient Pd-catalyzed modification of a picolinic acid derivative is presented.

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