Solid phase asymmetric alkylation reactions using 2-imidazolidinone chiral auxiliary
QPB Nguyen, JN Kim, TH Kim
Index: Nguyen, Quynh Pham Bao; Kim, Jae Nyoung; Kim, Taek Hyeon Tetrahedron Letters, 2009 , vol. 50, # 28 p. 4015 - 4018
Full Text: HTML
Citation Number: 13
Abstract
A novel solid supported 2-imidazolidinone chiral auxiliary was prepared from O-benzyl-l- tyrosine and Wang resin. Asymmetric alkylation reactions in the solid phase proceeded with excellent stereoselectivities, which were even higher than those observed in the conventional solution phase method.
Related Articles:
[Richter, Jeremy M.; Whitefield, Brandon W.; Maimone, Thomas J.; Lin, David W.; Castroviejo, M. Pilar; Baran, Phil S. Journal of the American Chemical Society, 2007 , vol. 129, # 42 p. 12857 - 12869]
[Caplar, Vesna; Raza, Zlata; Katalenic, Darinka; Zinic, Mladen Croatica Chemica Acta, 2003 , vol. 76, # 1 p. 23 - 36]
[Oila, Markku J.; Tois, Jan E.; Koskinen, Ari M.P. Tetrahedron, 2005 , vol. 61, # 45 p. 10748 - 10756]
[Oila, Markku J.; Tois, Jan E.; Koskinen, Ari M.P. Tetrahedron, 2005 , vol. 61, # 45 p. 10748 - 10756]
[Oila, Markku J.; Tois, Jan E.; Koskinen, Ari M.P. Tetrahedron, 2005 , vol. 61, # 45 p. 10748 - 10756]