One-pot synthesis of ketones from carboxylic acids and grignard reagents using N, N-Diphenyl-p-methoxyphenylchloromethyleniminium chloride

T Fujisawa, T Mori, T Sato

Index: Fujisawa, Tamotsu; Mori, Toshiki; Sato, Toshio Tetrahedron Letters, 1982 , vol. 23, # 48 p. 5059 - 5062

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Citation Number: 8

Abstract

In general, a condensation reaction most frequently used to prepare ketones In the laboratory 1s the reaction of organometalllcs with acylating reagents. As the latter reagents, acid halides,' esters,' acid anhydrldes,3 nitriles,' N-acyl- ~m~daz.oles,s 2-pylidllthloesters,6 and 8-acyloxyquinolines7 are employed and in some cases carboxylic acids themselves are used. Other starting materials are various kinds of organometalllcs constructing from ...