Replacing a stoichiometric silver oxidant with air: ligated Pd (II)-catalysis to β-aryl carbonyl derivatives with improved chemoselectivity

M Vellakkaran, MMS Andappan, N Kommu

Index: Vellakkaran, Mari; Andappan, Murugaiah M.S.; Kommu, Nagaiah Green Chemistry, 2014 , vol. 16, # 5 p. 2788 - 2797

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Citation Number: 7

Abstract

Air was employed as a green reoxidant of Pd (0), replacing stoichiometric and toxic silver salt, in the chelation-controlled Pd (II)-modulated arylative enolization of prop-2-en-1-ols to acquire synthetically-important β-aryl carbonyl derivatives. This green approach, which didn't require acid or base, allowed the compatibility of a range of functionalities (inclusive of– I,–Br &–Cl), resulting in the construction of structurally-diverse dihydrochalcones, α-benzyl ...