On-resin click-glycoconjugation of peptoids
AS Norgren, C Budke, Z Majer, C Heggemann…
Index: Norgren, Anna S.; Budke, Carsten; Majer, Zsuzsa; Heggemann, Carolin; Koop, Thomas; Sewald, Norbert Synthesis, 2009 , # 3 p. 488 - 494
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Citation Number: 28
Abstract
Abstract Peptoids are unnatural peptide-like oligomers having the side-chain attached to the glycine nitrogen. In order to investigate how such oligomers are affected upon glycoconjugation, a series of glycosylated peptoids has been synthesized. The conjugation between glycosyl residue and peptoid was achieved by azide+ alkyne [3+ 2] cycloaddition (click reaction). The glycosylated peptoids were obtained by either stepwise assembly ...
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