RhCl 3/amine-catalyzed [2+ 2+ 2] cyclization of alkynes

K Yoshida, I Morimoto, K Mitsudo, H Tanaka

Index: Yoshida, Kenta; Morimoto, Ichiro; Mitsudo, Koichi; Tanaka, Hideo Tetrahedron, 2008 , vol. 64, # 24 p. 5800 - 5807

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Citation Number: 43

Abstract

The RhCl3· 3H2O/i-Pr2NEt-catalyzed [2+ 2+ 2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri-or hexa- substituted benzenes regioselectively in high yields. The [2+ 2+ 2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields.